Editorial: Genetic Modification of Cardiac Tissue
نویسندگان
چکیده
منابع مشابه
Cell Transplantation and Tissue Regeneration Safe Genetic Modification of Cardiac Stem Cells Using a Site-Specific Integration Technique
Background—Human cardiac progenitor cells (hCPCs) are a promising cell source for regenerative repair after myocardial infarction. Exploitation of their full therapeutic potential may require stable genetic modification of the cells ex vivo. Safe genetic engineering of stem cells, using facile methods for site-specific integration of transgenes into known genomic contexts, would significantly e...
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See article by Kiriazis and Gibbs [1] (pages 111 –119) two parts, activation and basal oxygen consumption. The in this issue. first depends on excitation–contraction coupling and is proportional to cardiac contractility. For the quiescent muscle the PVA and the oxygen cost of activation both are zero. The remaining part results from all other processes 1. Work output and efficiency of the heart...
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15 صفحه اولGenetic Modification of T Cells
Gene transfer technology has advanced rapidly from simple physical-chemical laboratory methods in the 1970s and 1980s to the sophisticated viral and nonviral methods currently in clinical practice. Herein, we review 4 gene transfer methodologies applied in human gene therapy clinical trials transferring chimeric antigen receptors into T cells for the treatment of B-cell malignancies. The 4 meth...
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ژورنال
عنوان ژورنال: Frontiers in Cardiovascular Medicine
سال: 2019
ISSN: 2297-055X
DOI: 10.3389/fcvm.2019.00093